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Natural Diterpenoid Oridonin Ameliorates Experimental Autoimmune Neuritis by Promoting Anti-inflammatory Macrophages Through Blocking Notch Pathway

The diterpenoid compound, Oridonin, extracted from the Chinese herb, Rabdosia rubescens, possesses multiple biological activities and properties. Oridonin exhibited efficient anti-inflammatory activity by inducing a switch in macrophage polarization to the anti-inflammatory phenotype through inhibit...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Xu, Lu, Li, Lei, Zhang, Chen-Yang, Schluesener, Hermann, Zhang, Zhi-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454011/
https://ncbi.nlm.nih.gov/pubmed/31001070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00272
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