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SNAREs define targeting specificity of trafficking vesicles by combinatorial interaction with tethering factors

Membrane traffic operates by vesicles that bud from precursor organelles and are transported to their target compartment where they dock and fuse. Targeting requires tethering factors recruited by small GTPases and phosphoinositides whereas fusion is carried out by SNARE proteins. Here we report tha...

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Publicat a:Nat Commun
Autors principals: Koike, Seiichi, Jahn, Reinhard
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453939/
https://ncbi.nlm.nih.gov/pubmed/30962439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09617-9
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