TMCO1-mediated Ca(2+) leak underlies osteoblast functions via CaMKII signaling

Transmembrane and coiled-coil domains 1 (TMCO1) is a recently identified Ca(2+) leak channel in the endoplasmic reticulum. TMCO1 dysfunction in humans is associated with dysmorphism, mental retardation, glaucoma and the occurrence of cancer. Here we show an essential role of TMCO1 in osteogenesis me...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Li, Jianwei, Liu, Caizhi, Li, Yuheng, Zheng, Qiaoxia, Xu, Youjia, Liu, Beibei, Sun, Weijia, Li, Yuan, Ji, Shuhui, Liu, Mingwei, Zhang, Jing, Zhao, Dingsheng, Du, Ruikai, Liu, Zizhong, Zhong, Guohui, Sun, Cuiwei, Wang, Yanqing, Song, Jinping, Zhang, Shu, Qin, Jun, Ling, Shukuan, Wang, Xianhua, Li, Yingxian
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453895/
https://ncbi.nlm.nih.gov/pubmed/30962442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09653-5
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki