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Metal-organic Framework Encapsulation Preserves the Bioactivity of Protein Therapeutics

Protein therapeutics are prone to lose their structure and bioactivity under various environmental stressors. Herein, we report a facile approach using a nanoporous material, zeolitic imidazolate framework-8 (ZIF-8), as an encapsulant for preserving the prototypic protein therapeutic, insulin, again...

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Detalhes bibliográficos
Publicado no:Adv Healthc Mater
Main Authors: Wang, Congzhou, Sudlow, Gail, Wang, Zheyu, Cao, Sisi, Jiang, Qisheng, Neiner, Alicia, Morrissey, Jeremiah J., Kharasch, Evan. D., Achilefu, Samuel, Singamaneni, Srikanth
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453541/
https://ncbi.nlm.nih.gov/pubmed/30369102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201800950
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