Identification of pharmacodynamic biomarker hypotheses through literature analysis with IBM Watson

BACKGROUND: Pharmacodynamic biomarkers are becoming increasingly valuable for assessing drug activity and target modulation in clinical trials. However, identifying quality biomarkers is challenging due to the increasing volume and heterogeneity of relevant data describing the biological networks th...

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Vydáno v:PLoS One
Hlavní autoři: Hatz, Sonja, Spangler, Scott, Bender, Andrew, Studham, Matthew, Haselmayer, Philipp, Lacoste, Alix M. B., Willis, Van C., Martin, Richard L., Gurulingappa, Harsha, Betz, Ulrich
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453528/
https://ncbi.nlm.nih.gov/pubmed/30958864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214619
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