Identification of pharmacodynamic biomarker hypotheses through literature analysis with IBM Watson

BACKGROUND: Pharmacodynamic biomarkers are becoming increasingly valuable for assessing drug activity and target modulation in clinical trials. However, identifying quality biomarkers is challenging due to the increasing volume and heterogeneity of relevant data describing the biological networks th...

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Udgivet i:PLoS One
Main Authors: Hatz, Sonja, Spangler, Scott, Bender, Andrew, Studham, Matthew, Haselmayer, Philipp, Lacoste, Alix M. B., Willis, Van C., Martin, Richard L., Gurulingappa, Harsha, Betz, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453528/
https://ncbi.nlm.nih.gov/pubmed/30958864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214619
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