Heat shock in C. elegans induces downstream of gene transcription and accumulation of double-stranded RNA

We observed that heat shock of Caenorhabditis elegans leads to the formation of nuclear double-stranded RNA (dsRNA) foci, detectable with a dsRNA-specific monoclonal antibody. These foci significantly overlap with nuclear HSF-1 granules. To investigate the molecular mechanism(s) underlying dsRNA foc...

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Udgivet i:PLoS One
Main Authors: Melnick, Marko, Gonzales, Patrick, Cabral, Joseph, Allen, Mary A., Dowell, Robin D., Link, Christopher D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453478/
https://ncbi.nlm.nih.gov/pubmed/30958820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206715
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