Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium

The compression of brain tissue by a tumour mass is believed to be a major cause of the clinical symptoms seen in patients with brain cancer. However, the biological consequences of these physical stresses on brain tissue are unknown. Here, via imaging studies in patients and by using mouse models o...

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Detalhes bibliográficos
Publicado no:Nat Biomed Eng
Main Authors: Seano, Giorgio, Nia, Hadi T., Emblem, Kyrre E., Datta, Meenal, Ren, Jun, Krishnan, Shanmugarajan, Kloepper, Jonas, Pinho, Marco C., Ho, William W., Ghosh, Mitrajit, Askoxylakis, Vasileios, Ferraro, Gino B., Riedemann, Lars, Gerstner, Elizabeth R., Batchelor, Tracy T., Wen, Patrick Y., Lin, Nancy U., Grodzinsky, Alan J., Fukumura, Dai, Huang, Peigen, Baish, James W., Padera, Timothy P., Munn, Lance L., Jain, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452896/
https://ncbi.nlm.nih.gov/pubmed/30948807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-018-0334-7
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