Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution

Human gastric pathogen Helicobacter pylori (H. pylori) is the primary risk factor for gastric cancer and is one of the most prevalent carcinogenic infectious agents. Vacuolating cytotoxin A (VacA) is a key virulence factor secreted by H. pylori and induces multiple cellular responses. Although struc...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Zhang, Kaiming, Zhang, Huawei, Li, Shanshan, Pintilie, Grigore D., Mou, Tung-Chung, Gao, Yuanzhu, Zhang, Qinfen, van den Bedem, Henry, Schmid, Michael F., Au, Shannon Wing Ngor, Chiu, Wah
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452728/
https://ncbi.nlm.nih.gov/pubmed/30894496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821959116
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