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Amyloid found in human cataracts with two-dimensional infrared spectroscopy

UV light and other factors damage crystallin proteins in the eye lens, resulting in cataracts that scatter light and affect vision. Little information exists about protein structures within these disease-causing aggregates. We examined postmortem lens tissue from individuals with and without catarac...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Alperstein, Ariel M., Ostrander, Joshua S., Zhang, Tianqi O., Zanni, Martin T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452718/
https://ncbi.nlm.nih.gov/pubmed/30894486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821534116
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