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Childhood adiposity, adult adiposity, and the ACE gene insertion/deletion polymorphism: evidence of gene—environment interaction effects on adult blood pressure and hypertension status in adulthood

BACKGROUND: Genetic variants may modify the associations of adiposity measures with blood pressure (BP) and hypertension. The insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene is an attractive candidate. AIMS: To examine interaction effects between I/D polymorphis...

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Bibliografiske detaljer
Udgivet i:J Hypertens
Main Authors: Sun, Cong, Ponsonby, Anne-Louise, Carlin, John B., Bui, Minh, Magnussen, Costan G., Burns, Trudy L., Lehtimaki, Terho, Wardrop, Nicole H., Juonala, Markus, Viikari, Jorma S.A., Venn, Alison J., Raitakari, Olli T., Dwyer, Terence
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452450/
https://ncbi.nlm.nih.gov/pubmed/29939946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000001816
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