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Microparticles from vascular endothelial growth factor pathway inhibitor-treated cancer patients mediate endothelial cell injury

Vascular endothelial growth factor pathway inhibitors (VEGFi), used as anti-angiogenic drugs to treat cancer are associated with cardiovascular toxicities through unknown molecular mechanisms. Endothelial cell-derived microparticles (ECMPs) are biomarkers of endothelial injury and are also functiona...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cardiovasc Res
Hauptverfasser: Neves, Karla B, Rios, Francisco J, Jones, Robert, Evans, Thomas Ronald Jeffry, Montezano, Augusto C, Touyz, Rhian M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452312/
https://ncbi.nlm.nih.gov/pubmed/30753341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvz021
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