The Injectable Contraceptive Medroxyprogesterone Acetate Attenuates Mycobacterium tuberculosis–Specific Host Immunity Through the Glucocorticoid Receptor

BACKGROUND: The effects of the widely used progestin-only injectable contraceptives, medroxyprogesterone acetate (MPA) and norethisterone acetate (NET-A), on host susceptibility to Mycobacterium tuberculosis (Mtb) are unknown. METHODS: We recruited human immunodeficiency virus–uninfected females, no...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Tomasicchio, Michele, Davids, Malika, Pooran, Anil, Theron, Grant, Smith, Liezel, Semple, Lynn, Meldau, Richard, Hapgood, Janet Patricia, Dheda, Keertan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452311/
https://ncbi.nlm.nih.gov/pubmed/30452655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy657
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