Human mAbs to Staphylococcus aureus IsdA Provide Protection Through Both Heme-Blocking and Fc-Mediated Mechanisms

The nutrient metal iron plays a key role in the survival of microorganisms. The iron-regulated surface determinant (Isd) system scavenges heme-iron from the human host, enabling acquisition of iron in iron-deplete conditions in Staphylococcus aureus during infection. The cell surface receptors IsdB...

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Bibliografski detalji
Izdano u:J Infect Dis
Glavni autori: Bennett, Monique R, Bombardi, Robin G, Kose, Nurgun, Parrish, Erica H, Nagel, Marcus B, Petit, Robert A, Read, Timothy D, Schey, Kevin L, Thomsen, Isaac P, Skaar, Eric P, Crowe, James E
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Major Articles and Brief Reports
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452300/
https://ncbi.nlm.nih.gov/pubmed/30496483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy635
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