Plasma Indoleamine 2,3-Dioxygenase Activity Is Associated With the Size of the Human Immunodeficiency Virus Reservoir in Patients Receiving Antiretroviral Therapy

BACKGROUND: Indoleamine 2,3-dioxygenase (IDO) is an immunoregulatory enzyme that metabolizes tryptophan to immunosuppressive kynurenines. We investigated whether IDO activity is associated with the size of HIV reservoir. METHODS: Total human immunodeficiency virus (HIV) DNA in peripheral blood monon...

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Dettagli Bibliografici
Pubblicato in:Clin Infect Dis
Autori principali: Chen, Jun, Xun, Jingna, Yang, Junyang, Ji, Yongjia, Liu, Li, Qi, Tangkai, Wang, Zhenyan, Zhang, Renfang, Shen, Yinzhong, Ponte, Rosalie, Mehraj, Vikram, Routy, Jean-Pierre, Lu, Hongzhou
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Articles and Commentaries
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451994/
https://ncbi.nlm.nih.gov/pubmed/30107503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy676
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