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The Contribution of Low-Frequency and Rare Coding Variation to Susceptibility to Type 2 Diabetes

PURPOSE OF REVIEW: Soon after the first genome-wide association study (GWAS) for type 2 diabetes (T2D) was published, it was hypothesized that rare and low-frequency variants might explain a substantial proportion of disease risk. Rare coding variants in particular were emphasized given their large...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Curr Diab Rep
1. Verfasser: Flannick, Jason
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451938/
https://ncbi.nlm.nih.gov/pubmed/30957210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11892-019-1142-5
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