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Synthesis, Characterization and Biological Studies of Rhenium, Technetium-99m and Rhenium-188 Pentapeptides: Synthesis of M-Pentapeptides (M= (nat)Re, (99m)Tc, (188)Re)

A pentapeptide macrocyclic ligand, KYCAR (lysyl-tyrosyl-cystyl-alanyl-arginine), has been designed as a potential chelating ligand for SPECT imaging and therapeutic in vivo agents. This study shows the synthesis and characterization of KYCAR complexes containing nonradioactive rhenium, (99m)Tc, or (...

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Detalhes bibliográficos
Publicado no:Nucl Med Biol
Main Authors: Sanders, Vanessa A., Iskhakov, David, Abdel-Atti, Dalya, Devany, Matthew, Neary, Michelle C, Czerwinski, Ken R., Francesconi, Lynn C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451878/
https://ncbi.nlm.nih.gov/pubmed/30578134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2018.11.001
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