Bi-allelic Mutations in TTC21A Induce Asthenoteratospermia in Humans and Mice

Male infertility is a major concern affecting human reproductive health. Asthenoteratospermia can cause male infertility through reduced motility and abnormal morphology of spermatozoa. Several genes, including DNAH1 and some CFAP family members, are involved in multiple morphological abnormalities...

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Veröffentlicht in:Am J Hum Genet
Hauptverfasser: Liu, Wangjie, He, Xiaojin, Yang, Shenmin, Zouari, Raoudha, Wang, Jiaxiong, Wu, Huan, Kherraf, Zine-Eddine, Liu, Chunyu, Coutton, Charles, Zhao, Rui, Tang, Dongdong, Tang, Shuyan, Lv, Mingrong, Fang, Youyan, Li, Weiyu, Li, Hong, Zhao, Jianyuan, Wang, Xue, Zhao, Shimin, Zhang, Jingjing, Arnoult, Christophe, Jin, Li, Zhang, Zhiguo, Ray, Pierre F., Cao, Yunxia, Zhang, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451729/
https://ncbi.nlm.nih.gov/pubmed/30929735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.02.020
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