Ready-to-use parenteral amiodarone: a feasibility study towards a long-term stable product formulation

OBJECTIVES: To determine the feasibility of preparing a long-term stable ready-to-use parenteral amiodarone formulation using cyclodextrins as dissolution enhancer. METHODS: A preformulation study was performed with different molar ratios of hydroxypropyl-beta-cyclodextrin (HP-BCD) or sulfobutylethe...

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Bibliografske podrobnosti
izdano v:Eur J Hosp Pharm
Main Authors: Jacobs, Maartje S, Luinstra, Marianne, Moes, Jan Reindert, Chan, Tiffany C Y, Minovic, Isidor, Frijlink, Henderik W, Woerdenbag, Herman J
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451646/
https://ncbi.nlm.nih.gov/pubmed/31156915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ejhpharm-2015-000860
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