Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

BACKGROUND: The mechanisms underpinning the regenerative capabilities of mesenchymal stem cells (MSC) were originally thought to reside in their ability to recognise damaged tissue and to differentiate into specific cell types that would replace defective cells. However, recent work has shown that m...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Mitchell, Robert, Mellows, Ben, Sheard, Jonathan, Antonioli, Manuela, Kretz, Oliver, Chambers, David, Zeuner, Marie-Theres, Tomkins, James E., Denecke, Bernd, Musante, Luca, Joch, Barbara, Debacq-Chainiaux, Florence, Holthofer, Harry, Ray, Steve, Huber, Tobias B., Dengjel, Joern, De Coppi, Paolo, Widera, Darius, Patel, Ketan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451311/
https://ncbi.nlm.nih.gov/pubmed/30953537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1213-1
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