Development of a glycoproteomic strategy to detect more aggressive prostate cancer using lectin-immunoassays for serum fucosylated PSA

BACKGROUND: Prostate-specific antigen (PSA) is commonly used as a serum biomarker for the detection of prostate cancer. However, levels of PSA in serum do not reliably distinguish aggressive prostate cancer from non-aggressive disease. Therefore, there is an urgent need for biomarkers that can diffe...

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Publicado en:Clin Proteomics
Autores principales: Wang, Ce, Höti, Naseruddin, Lih, Tung-Shing Mamie, Sokoll, Lori J., Zhang, Rui, Zhang, Zhen, Zhang, Hui, Chan, Daniel W.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451306/
https://ncbi.nlm.nih.gov/pubmed/30996714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12014-019-9234-4
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