Structural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila

In Drosophila, dosage compensation globally upregulates the expression of genes located on male single X-chromosome. Maleless (MLE) helicase plays an essential role to incorporate the roX lncRNA into the dosage compensation complex (MSL-DCC), and such function is essentially dependent on its dsRNA-b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lv, Mengqi, Yao, Yixiang, Li, Fudong, Xu, Ling, Yang, Lingna, Gong, Qingguo, Xu, Yong-Zhen, Shi, Yunyu, Fan, Yu-Jie, Tang, Yajun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451107/
https://ncbi.nlm.nih.gov/pubmed/30649456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1308
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados