Targeting the phosphorylation site of myristoylated alanine‐rich C kinase substrate alleviates symptoms in a murine model of steroid‐resistant asthma

BACKGROUND AND PURPOSE: Myristoylated alanine‐rich C kinase substrate (MARCKS), a PKC substrate, facilitates mucus production and neutrophil migration. However, the effects of therapeutic procedures targeting the phosphorylation site of MARCKS on steroid‐resistant asthma and the mechanisms underlyin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Pharmacol
Main Authors: Wang, Chien‐Neng, Lin, Yu‐Chao, Chang, Bo‐Chun, Chen, Ching‐Hsien, Wu, Reen, Lee, Chen‐Chen
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451065/
https://ncbi.nlm.nih.gov/pubmed/30706455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14596
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