Perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy

Hypoxia-based agents (HBAs), such as anaerobic bacteria and bioreductive prodrugs, require both a permeable and hypoxic intratumoural environment to be fully effective. To solve this problem, herein, we report that perfluorocarbon nanoparticles (PNPs) can be used to create a long-lasting, penetrable...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Wang, Wenguang, Cheng, Yuhao, Yu, Peng, Wang, Haoran, Zhang, Yue, Xu, Haiheng, Ye, Qingsong, Yuan, Ahu, Hu, Yiqiao, Wu, Jinhui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450981/
https://ncbi.nlm.nih.gov/pubmed/30952842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09389-2
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