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Perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy
Hypoxia-based agents (HBAs), such as anaerobic bacteria and bioreductive prodrugs, require both a permeable and hypoxic intratumoural environment to be fully effective. To solve this problem, herein, we report that perfluorocarbon nanoparticles (PNPs) can be used to create a long-lasting, penetrable...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450981/ https://ncbi.nlm.nih.gov/pubmed/30952842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09389-2 |
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