β-Adrenergic Receptor Stimulation and Alternans in the Border Zone of a Healed Infarct: An ex vivo Study and Computational Investigation of Arrhythmogenesis

Background: Following myocardial infarction (MI), the myocardium is prone to calcium-driven alternans, which typically precedes ventricular tachycardia and fibrillation. MI is also associated with remodeling of the sympathetic innervation in the infarct border zone, although how this influences arrh...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Tomek, Jakub, Hao, Guoliang, Tomková, Markéta, Lewis, Andrew, Carr, Carolyn, Paterson, David J., Rodriguez, Blanca, Bub, Gil, Herring, Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450465/
https://ncbi.nlm.nih.gov/pubmed/30984029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00350
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