Co-Delivery of Timolol and Brimonidine with a Polymer Thin-Film Intraocular Device

Purpose: We developed a polycaprolactone (PCL) co-delivery implant that achieves zero-order release of 2 ocular hypotensive agents, timolol maleate and brimonidine tartrate. We also demonstrate intraocular pressure (IOP)-lowering effects of the implant for 3 months in vivo. Methods: Two PCL thin-fil...

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Detaylı Bibliyografya
Yayımlandı:J Ocul Pharmacol Ther
Asıl Yazarlar: Samy, Karen E., Cao, Yiqi, Kim, Jean, Konichi da Silva, Nina Rosa, Phone, Audrey, Bloomer, Michele M., Bhisitkul, Robert B., Desai, Tejal A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc., publishers 2019
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450452/
https://ncbi.nlm.nih.gov/pubmed/30615539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2018.0096
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