Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria

Cerebral malaria is a leading cause of global morbidity and mortality. Interventions targeting the underlying pathophysiology of cerebral malaria may improve outcomes compared to treatment with antimalarials alone. Microvascular leak plays an important role in the pathogenesis of cerebral malaria. T...

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Vydáno v:Sci Transl Med
Hlavní autoři: Higgins, Sarah J., Purcell, Lisa A., Silver, Karlee L., Tran, Vanessa, Crowley, Valerie, Hawkes, Michael, Conroy, Andrea L., Opoka, Robert O., Hay, John G., Quaggin, Susan E., Thurston, Gavin, Liles, W. Conrad, Kain, Kevin C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450386/
https://ncbi.nlm.nih.gov/pubmed/27683553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf6812
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