Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria

Cerebral malaria is a leading cause of global morbidity and mortality. Interventions targeting the underlying pathophysiology of cerebral malaria may improve outcomes compared to treatment with antimalarials alone. Microvascular leak plays an important role in the pathogenesis of cerebral malaria. T...

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Dades bibliogràfiques
Publicat a:Sci Transl Med
Autors principals: Higgins, Sarah J., Purcell, Lisa A., Silver, Karlee L., Tran, Vanessa, Crowley, Valerie, Hawkes, Michael, Conroy, Andrea L., Opoka, Robert O., Hay, John G., Quaggin, Susan E., Thurston, Gavin, Liles, W. Conrad, Kain, Kevin C.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450386/
https://ncbi.nlm.nih.gov/pubmed/27683553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf6812
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