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Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria

Cerebral malaria is a leading cause of global morbidity and mortality. Interventions targeting the underlying pathophysiology of cerebral malaria may improve outcomes compared to treatment with antimalarials alone. Microvascular leak plays an important role in the pathogenesis of cerebral malaria. T...

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Bibliografiske detaljer
Udgivet i:Sci Transl Med
Main Authors: Higgins, Sarah J., Purcell, Lisa A., Silver, Karlee L., Tran, Vanessa, Crowley, Valerie, Hawkes, Michael, Conroy, Andrea L., Opoka, Robert O., Hay, John G., Quaggin, Susan E., Thurston, Gavin, Liles, W. Conrad, Kain, Kevin C.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450386/
https://ncbi.nlm.nih.gov/pubmed/27683553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf6812
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