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INTERVAL ESTIMATORS OF RELATIVE POTENCY IN TOXICOLOGY AND RADIATION COUNTERMEASURE STUDIES: COMPARING METHODS AND EXPERIMENTAL DESIGNS

The relative potency of one agent to another is commonly represented by the ratio of two quantal response parameters; for example, the LD(50) of animals receiving a treatment to the LD(50) of control animals, where LD(50) is the dose of toxin that is lethal to 50% of animals. Though others have cons...

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Detalhes bibliográficos
Publicado no:J Biopharm Stat
Main Authors: Landes, Reid D., Lensing, Shelly Y., Hauer-Jensen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450382/
https://ncbi.nlm.nih.gov/pubmed/30352015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2018.1535500
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