Commensal and Pathogenic Bacteria Indirectly Induce IL-22 but Not IFNγ Production From Human Colonic ILC3s via Multiple Mechanisms

Innate lymphoid cells (ILCs) are a diverse family of cells that play critical roles in mucosal immunity. One subset of the ILC family, Group 3 ILCs (ILC3s), has been shown to aid in gut homeostasis through the production of IL-22. IL-22 promotes gut homeostasis through its functional effect on the e...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Castleman, Moriah J., Dillon, Stephanie M., Purba, Christine M., Cogswell, Andrew C., Kibbie, Jon J., McCarter, Martin D., Santiago, Mario L., Barker, Edward, Wilson, Cara C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450192/
https://ncbi.nlm.nih.gov/pubmed/30984202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00649
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