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Generation of Infectious Recombinant Human Rotaviruses from Just 11 Cloned cDNAs Encoding the Rotavirus Genome

The generation of recombinant group A rotaviruses (RVAs) entirely from cloned cDNAs has been described only for a single animal RVA strain, simian SA11-L2. We recently developed an optimized RVA reverse genetics system based on only RVA cDNAs (11-plasmid system), in which the concentration of cDNA p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Komoto, Satoshi, Fukuda, Saori, Kugita, Masanori, Hatazawa, Riona, Koyama, Chitose, Katayama, Kazuhiko, Murata, Takayuki, Taniguchi, Koki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450123/
https://ncbi.nlm.nih.gov/pubmed/30728265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02207-18
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