Double Positive CD4(+)CD8(+) T Cells Are Enriched in Urological Cancers and Favor T Helper-2 Polarization

The immune system plays a central role in cancer development, showing both anti-tumor and pro-tumor activities depending on the immune cell subsets and the disease context. While CD8 T cells are associated with a favorable outcome in most cancers, only T helper type 1 (Th1) CD4 T cells play a protec...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bohner, Perrine, Chevalier, Mathieu F., Cesson, Valérie, Rodrigues-Dias, Sonia-Christina, Dartiguenave, Florence, Burruni, Rodolfo, Tawadros, Thomas, Valerio, Massimo, Lucca, Ilaria, Nardelli-Haefliger, Denise, Jichlinski, Patrice, Derré, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450069/
https://ncbi.nlm.nih.gov/pubmed/30984190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00622
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