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Coping with strong translational noncrystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a

Data pathologies caused by effects such as diffraction anisotropy and translational noncrystallographic symmetry (tNCS) can dramatically complicate the solution of the crystal structures of macromolecules. Such problems were encountered in determining the structure of a mutant form of Rab27a, a memb...

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Bibliografske podrobnosti
izdano v:Acta Crystallogr D Struct Biol
Main Authors: Jamshidiha, Mostafa, Pérez-Dorado, Inmaculada, Murray, James W., Tate, Edward W., Cota, Ernesto, Read, Randy J.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450061/
https://ncbi.nlm.nih.gov/pubmed/30950405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798318017825
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