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Combined Gene and Protein Expression of Hormone-Sensitive Lipase and Adipose Triglyceride Lipase, Mitochondrial Content, and Adipocyte Size in Subcutaneous and Visceral Adipose Tissue of Morbidly Obese Men

AIMS: Lipotoxicity in obesity might be a failure of adipocytes to respond sufficiently adequate to persistent energy surplus. To evaluate the role of lipolytic enzymes or mitochondria in lipotoxicity, we studied expression levels of genes and proteins involved in lipolysis and mitochondrial DNA (mtD...

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Detalhes bibliográficos
Publicado no:Obes Facts
Main Authors: De Naeyer, Hélène, Ouwens, D. Margriet, Van Nieuwenhove, Yves, Pattyn, Piet, ‘t Hart, Leen M., Kaufman, Jean-Marc, Sell, Henrike, Eckel, Juergen, Cuvelier, Claude, Taes, Youri E., Ruige, Johannes B.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450043/
https://ncbi.nlm.nih.gov/pubmed/22166762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000333445
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