Anti-CNTN1 IgG3 induces acute conduction block and motor deficits in a passive transfer rat model

BACKGROUND: Autoantibodies against the paranodal protein contactin-1 have recently been described in patients with severe acute-onset autoimmune neuropathies and mainly belong to the IgG4 subclass that does not activate complement. IgG3 anti-contactin-1 autoantibodies are rare, but have been detecte...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Neuroinflammation
Main Authors: Doppler, Kathrin, Schuster, Yasmin, Appeltshauser, Luise, Biko, Lydia, Villmann, Carmen, Weishaupt, Andreas, Werner, Christian, Sommer, Claudia
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450014/
https://ncbi.nlm.nih.gov/pubmed/30953561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1462-z
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