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Fusing gene expressions and transitive protein-protein interactions for inference of gene regulatory networks

BACKGROUND: Systematic fusion of multiple data sources for Gene Regulatory Networks (GRN) inference remains a key challenge in systems biology. We incorporate information from protein-protein interaction networks (PPIN) into the process of GRN inference from gene expression (GE) data. However, exist...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Liu, Wenting, Rajapakse, Jagath C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449891/
https://ncbi.nlm.nih.gov/pubmed/30953534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-019-0695-x
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