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Predicting disease-related phenotypes using an integrated phenotype similarity measurement based on HPO

BACKGROUND: Improving efficiency of disease diagnosis based on phenotype ontology is a critical yet challenging research area. Recently, Human Phenotype Ontology (HPO)-based semantic similarity has been affectively and widely used to identify causative genes and diseases. However, current phenotype...

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Dades bibliogràfiques
Publicat a:BMC Syst Biol
Autors principals: Xue, Hansheng, Peng, Jiajie, Shang, Xuequn
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449884/
https://ncbi.nlm.nih.gov/pubmed/30953559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-019-0697-8
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