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Drug Gene Budger (DGB): an application for ranking drugs to modulate a specific gene based on transcriptomic signatures

SUMMARY: Mechanistic molecular studies in biomedical research often discover important genes that are aberrantly over- or under-expressed in disease. However, manipulating these genes in an attempt to improve the disease state is challenging. Herein, we reveal Drug Gene Budger (DGB), a web-based and...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Wang, Zichen, He, Edward, Sani, Kevin, Jagodnik, Kathleen M, Silverstein, Moshe C, Ma’ayan, Avi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449747/
https://ncbi.nlm.nih.gov/pubmed/30169739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty763
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