CSF Free Light Chains as a Marker of Intrathecal Immunoglobulin Synthesis in Multiple Sclerosis: A Blood-CSF Barrier Related Evaluation in a Large Cohort

Objectives: The importance of immunoglobulin G (IgG) oligoclonal bands (OCB) in the diagnosis of multiple sclerosis (MS) was reaffirmed again in the recently revised MS diagnostic criteria. Since OCB testing is based on non-quantitative techniques and demands considerable methodological experience,...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Senel, Makbule, Mojib-Yezdani, Fatemeh, Braisch, Ulrike, Bachhuber, Franziska, Lewerenz, Jan, Ludolph, Albert C., Otto, Markus, Tumani, Hayrettin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449445/
https://ncbi.nlm.nih.gov/pubmed/30984199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00641
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