NKG2D/NKG2-Ligand Pathway Offers New Opportunities in Cancer Treatment

The antitumor functions of NK cells are regulated by the integration of positive and negative signals triggered by numerous membrane receptors present on the NK cells themselves. Among the main activating receptors, NKG2D binds several stress-induced molecules on tumor targets. Engagement of NKG2D b...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Frazao, Alexandra, Rethacker, Louise, Messaoudene, Meriem, Avril, Marie-Françoise, Toubert, Antoine, Dulphy, Nicolas, Caignard, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449444/
https://ncbi.nlm.nih.gov/pubmed/30984204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00661
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