Glucocorticoid-resistant B cell acute lymphoblastic leukemia displays receptor tyrosine kinase activation

The response of childhood acute lymphoblastic leukemia (ALL) to dexamethasone predicts the long-term remission outcome. To explore the mechanisms of dexamethasone resistance in B cell ALL (B-ALL), we generated dexamethasone-resistant clones by prolonged treatment with dexamethasone. Using RNA-sequen...

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Enregistré dans:
Détails bibliographiques
Publié dans:NPJ Genom Med
Auteurs principaux: Chougule, Rohit A., Shah, Kinjal, Moharram, Sausan A., Vallon-Christersson, Johan, Kazi, Julhash U.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Brief Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449402/
https://ncbi.nlm.nih.gov/pubmed/30962949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-019-0082-y
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