Ferroptosis contributes to neuronal death and functional outcome after traumatic brain injury.

OBJECTIVES: Traumatic brain injury (TBI) triggers multiple cell death pathways, possibly including ferroptosis – a recently described cell death pathway that results from accumulation of 15-lipoxygenase (15-LOX)-mediated lipid oxidation products, specifically oxidized phosphatidylethanolamine (PE) c...

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Publicado no:Crit Care Med
Main Authors: Kenny, Elizabeth M., Fidan, Emin, Yang, Qin, Anthonymuthu, Tamil S., New, Lee Ann, Meyer, Elizabeth A., Wang, Hong, Kochanek, Patrick M., Dixon, C. Edward, Kagan, Valerian E., Bayır, Hülya
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449247/
https://ncbi.nlm.nih.gov/pubmed/30531185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000003555
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