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Comprehensive analysis of circular RNA profiling in AZD9291‐resistant non‐small cell lung cancer cell lines

BACKGROUND: Osimertinib (AZD9291), a third‐generation EGFR‐tyrosine kinase inhibitor, can effectively prolong survival in non‐small cell lung cancer (NSCLC) patients with EGFR mutations, particularly T790M mutations; however, acquired resistance to AZD9291 is inevitable, thus exploration of the targ...

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Détails bibliographiques
Publié dans:Thorac Cancer
Auteurs principaux: Chen, Tianxiang, Luo, Jizhuang, Gu, Yu, Huang, Jia, Luo, Qingquan, Yang, Yunhai
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons Australia, Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449233/
https://ncbi.nlm.nih.gov/pubmed/30883029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13032
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