Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort.

Sickle cell disease (SCD) is the most common monogenic disorder in the world. Notably, there is extensive clinical heterogeneity in SCD that cannot be fully accounted for by known factors, and in particular, the extent to which the phenotypic diversity of SCD can be explained by genetic variation ha...

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Vydáno v:Am J Hematol
Hlavní autoři: Bao, Erik L., Lareau, Caleb A., Brugnara, Carlo, Fulcher, Isabel, Barau, Caroline, Moutereau, Stephane, Habibi, Anoosha, Badaoui, Bouchra, Berkenou, Jugurtha, Bartolucci, Pablo, Galactéros, Frédéric, Platt, Orah S., Mahaney, Michael, Sankaran, Vijay G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449202/
https://ncbi.nlm.nih.gov/pubmed/30680775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25421
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