Cytokines Produced by Dendritic Cells Administered Intratumorally Correlate with Clinical Outcome in Patients with Diverse Cancers

PURPOSE: Dendritic cells (DCs) initiate adaptive immune responses through the uptake and presentation of antigenic material. In preclinical studies, intratumorally injected activated DCs (aDCs; DCVax®-Direct) were superior to immature DCs in rejecting tumors from mice. EXPERIMENTAL DESIGN: This sing...

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Pubblicato in:Clin Cancer Res
Autori principali: Subbiah, Vivek, Murthy, Ravi, Hong, David S., Prins, Robert M., Hosing, Chitra, Hendricks, Kyle, Kolli, Deepthi, Noffsinger, Lori, Brown, Robert, McGuire, Mary, Fu, Siquing, Piha-Paul, Sarina, Naing, Aung, Conley, Anthony P., Benjamin, Robert S, Kaur, Indreshpal, Bosch, Marnix L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449174/
https://ncbi.nlm.nih.gov/pubmed/30018119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2707
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