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Actin-binding domains mediate the distinct distribution of two Dictyostelium Talins through different affinities to specific subsets of actin filaments during directed cell migration

Although the distinct distribution of certain molecules along the anterior or posterior edge is essential for directed cell migration, the mechanisms to maintain asymmetric protein localization have not yet been fully elucidated. Here, we studied a mechanism for the distinct localizations of two Dic...

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Veröffentlicht in:PLoS One
Hauptverfasser: Tsujioka, Masatsune, Uyeda, Taro Q. P., Iwadate, Yoshiaki, Patel, Hitesh, Shibata, Keitaro, Yumoto, Tenji, Yonemura, Shigenobu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449030/
https://ncbi.nlm.nih.gov/pubmed/30946777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214736
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