A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka

Dmrt1 is a highly conserved transcription factor, which is critically involved in regulation of gonad development of vertebrates. In medaka, a duplicate of dmrt1—acting as master sex-determining gene—has a tightly timely and spatially controlled gonadal expression pattern. In addition to transcripti...

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Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: Herpin, Amaury, Schmidt, Cornelia, Kneitz, Susanne, Gobé, Clara, Regensburger, Martina, Le Cam, Aurélie, Montfort, Jérome, Adolfi, Mateus C., Lillesaar, Christina, Wilhelm, Dagmar, Kraeussling, Michael, Mourot, Brigitte, Porcon, Béatrice, Pannetier, Maëlle, Pailhoux, Eric, Ettwiller, Laurence, Dolle, Dirk, Guiguen, Yann, Schartl, Manfred
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448818/
https://ncbi.nlm.nih.gov/pubmed/30947255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000185
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