Upregulation of Human Glycolipid Transfer Protein (GLTP) Induces Necroptosis in Colon Carcinoma Cells

Human GLTP on chromosome 12 (locus 12q24.11) encodes a 24 kD amphitropic lipid transfer protein (GLTP) that mediates glycosphingolipid (GSL) intermembrane trafficking and regulates GSL homeostatic levels within cells. Herein, we provide evidence that GLTP overexpression inhibits the growth of human...

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Bibliographic Details
Published in:Biochim Biophys Acta Mol Cell Biol Lipids
Main Authors: Mishra, Shrawan Kumar, Stephenson, Daniel J., Chalfant, Charles E., Brown, Rhoderick E.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448591/
https://ncbi.nlm.nih.gov/pubmed/30472325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.11.002
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