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Cortical cholinergic denervation in primary progressive aphasia with Alzheimer pathology

OBJECTIVE: To investigate the status of the basal forebrain cholinergic system in primary progressive aphasia (PPA) as justification for cholinergic therapy. METHODS: A cohort of 36 brains from PPA participants with the neuropathology of Alzheimer disease (PPA-AD, n = 14) or frontotemporal lobar deg...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Mesulam, M.-Marsel, Lalehzari, Nava, Rahmani, Farzan, Ohm, Daniel, Shahidehpour, Ryan, Kim, Garam, Gefen, Tamar, Weintraub, Sandra, Bigio, Eileen, Geula, Changiz
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448447/
https://ncbi.nlm.nih.gov/pubmed/30842294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000007247
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