(p)NNS-Conjugated Chitosan Mediated IGF-1 and miR-140 Overexpression in Articular Chondrocytes Improves Cartilage Repair

The aim of the present study was to investigate the effects of phosphorylatable nucleus localization signal linked nucleic kinase substrate short peptide ((p)NNS)-conjugated chitosan ((p)NNS-CS) mediated miR-140 and IGF-1 in both rabbit chondrocytes and cartilage defects model. (p)NNS-CS was combine...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Zhao, Rong-lan, Zhang, Xu-mei, Jia, Li-na, Song, Wei, Sun, Yan-li, Meng, Xiang-ying, Peng, Xiao-xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448336/
https://ncbi.nlm.nih.gov/pubmed/31016187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2761241
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