Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability

BACKGROUND: The increasing use of gold nanoparticles (AuNPs) in the field of neuroscience instilled hope for their rapid translation to the clinical practice. AuNPs can be engineered to carry therapeutics or diagnostics in the diseased brain, possibly providing greater cell specificity and low toxic...

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Veröffentlicht in:J Nanobiotechnology
Hauptverfasser: Spinelli, Antonello, Girelli, Maria, Arosio, Daniela, Polito, Laura, Podini, Paola, Martino, Gianvito, Seneci, Pierfausto, Muzio, Luca, Menegon, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448280/
https://ncbi.nlm.nih.gov/pubmed/30943991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0481-3
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