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Molecular and serological characterization of hepatitis B vaccine breakthrough infections in serial samples from two plasma donors

BACKGROUND: Although vaccines for hepatitis B virus (HBV) are highly effective, HBV infections in vaccinees occur. Index samples of breakthrough infections are typically anti-HBc negative but HBV DNA positive with protective anti-HBs levels while HBsAg detection may be delayed or absent. HBsAg mutat...

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Détails bibliographiques
Publié dans:Virol J
Auteurs principaux: Kuhns, Mary C., McNamara, Anne L., Holzmayer, Vera, Cloherty, Gavin A.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448254/
https://ncbi.nlm.nih.gov/pubmed/30943997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-019-1154-4
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